“I honestly believe my husband and I are alive today because of the diligent and caring medical care and superior interpretive analysis skills of Dr. Keri Topouzian. Dr. Topouzian demands the best for his patients. The blood tests are extremely thorough and very revealing as our bodies change and age. The compounded medications for our thyroid and hormonal issues have been so much better assimilated by our bodies over [over the use of] pharmaceutical drugs. My husband and I feel better with Dr. Topouzian’s more natural approach to our health. If you don’t have your health how can you enjoy anything else?”
In premenopausal women the majority of estrogen produced by the body is estradiol (produced primarily in the ovaries), while in postmenopausal women estrone (produced in fat cells) is the type of estrogen present in the greatest amount; however, the body is able to convert one type of estrogen into another to a certain extent. Because of the limited research into potency, delivery methods and conversion of the various estrogens, a valid scientific understanding of compounded estrogen products has not been achieved.  Synthetic estradiol, taken orally, splits when absorbed in the gastrointestinal tract and delivers bioidentical estradiol to the bloodstream. 
Bioidentical hormones have the same chemical structure as hormones produced in the human body. There have been many studies demonstrating their safety. At this time, with the ready availability of bioidentical hormones, there is no reason to use non-human formulations. There is a track record of benefit and safety for women taking controlled doses of these hormones, in carefully selected formulations, under medical supervision. Horse hormones and progestins for hormone replacement should become obsolete. Patient demand will make this happen.