Norplant was used internationally beginning in 1983 and was marketed in the United States and the United Kingdom in 1993. There were many complications associated with Norplant insertion and removal in the United States and it was taken off the market in 2002. Although Jadelle was approved by the FDA, it has never been marketed in the United States, but it is widely used in Africa and Asia.  Implanon was first used in Indonesia in 1998 and approved for use in the United States in 2006. Nexplanon was developed to eliminate the problem of non-insertion and localization of Implanon by changing the inserter device and making the rod radiopaque.  Nexplanon has replaced Implanon in the UK because of cases of incorrect insertion. As of January 2012, Implanon is no longer being marketed in the US, and Nexplanon is the only available single-rod implant.
What is it? An anabolic steroid (a steroid that acts as the hormone testosterone) that occurs in small amounts in the human body.
Medical Use: Used to treat osteoporosis in postmenopausal women, to aid in the growth of blood cells in bone marrow, and to help tissue and muscle growth in people suffering from degenerative diseases like AIDS.
Athletic Use: To grow muscle mass and aid in physical recovery from workouts.
Possible Negative Side Effects: Cardiovascular damage, sexual dysfunction, liver damage, acne, sterility, baldness, enlarged prostate.
Is it legal? Available only by prescription.
In 2009, the committee of scientific experts of the Stockholm Convention concluded, "endosulfan is likely, as a result of long range environmental transport, to lead to significant adverse human health and environmental effects such that global action is warranted."  In May 2011, the Stockholm Convention committee approved the recommendation for elimination of production and use of endosulfan and its isomers worldwide. This is, however, subject to certain exemptions. Overall, this will lead to its elimination from the global markets.