The Journal of American Medical Association released a 1998 review stating that s aw palmetto is effective in improving urological symptoms and urine flow . For the review, 18 randomized trials with almost 3,000 male participants were analyzed; 28 percent of the men taking saw palmetto showed fewer urinary tract symptoms, 24 percent showed improvement in peak urine flow and overall urine flow improved for 43 percent of the participants. The results were comparable to the group taking Proscar — a prescribed medication — and they were much more promising than the men taking a placebo.
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A study assessing the affects of several herbal medications including saw palmetto on platelet function in adult volunteers found no effect of saw palmetto on platelets after 2 weeks at the recommended dose. 47 However, there has been 1 case report linking saw palmetto to intraoperative hemorrhage. 48 A 53-year-old white man with normal preoperative prothrombin time and activated partial thromboplastin time underwent surgical resection of meningioma. Surgery was terminated early after administration of 4 liters of crystalloid fluids, 4r units of packed red blood cells, 3 units of pooled platelets, and 3 units of fresh frozen plasma. After surgery, the patient had an elevated bleeding time, which normalized over the next 5 days. No other medication use or events were reported that could be linked to the elevated bleeding time; saw palmetto dose, duration of therapy, or manufacturer were not reported in the case report.